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Key Faculty: Steven Markowitz, MD (Associate Professor)
This ongoing project utilizes new cardiac imaging modalities, such as 3-dimensional echocardiography, MRI, and PET scanning, to distinguish idiopathic ventricular tachycardia from right ventricular cardiomyopathies and to better understand the mechanism of outflow tract tachycardias.
Selected References
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Markowitz SM, Litvak BL,
Ramirez de Arellano EA, Markisz JA, Stein KM, Lerman BB.
Adenosine-sensitive ventricular tachycardia: Right ventricular
abnormalities delineated by magnetic resonance imaging. Circulation. 1997;96:1192-1200.
Evaluation of the Prevalence of Abnormal Coronary Perfusion Studies in Patients with Transient Ischemic Attack (TIA) and/or Ischemic Stroke.
Key Faculty: Jonathan Weinsaft, MD, Franklin Wong, MD, Massimiliano Szulc, PhD
The aim of the study is to establish whether major or minor strokes can be considered a predictor of concomitant coronary disease. This study is being carried out by Cardiology Fellow Christopher Chen, MD.
The Incremental Value of Attenuation Correction on the Diagnostic Accuracy of Stress Radionuclide Myocardial Perfusion Imaging.
Key Faculty: Jonathan Weinsaft, MD (Assistant Professor), Franklin Wong, MD (Assistant Professor), Massimiliano Szulc, PhD (Assistant Professor)
The aim of the study is to assess the effect of attenuation correction (specifically obtained with the aid of concomitant transmission imaging from a traveling line source of Gd-153) on the interpretation of stress myocardial perfusion images. Enhanced accuracy will permit better identification of patients at higher risk of adverse cardiac events.
Selected References
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Igor Klem, John Heitner, Dipan Shah, Michael Sketch,
Victor Behar, Jonathan Weinsaft, Peter Cawley, Michele Parker,
Michael Elliott, Robert Judd, Raymond Kim. Improved Detection of
Coronary Artery Disease by Stress Perfusion Cardiovascular Magnetic
Resonance with the use of Delayed Enhancement Infarction Imaging.
Circulation. (in review)
Weinsaft J, Kim H, Klem I, Velazquez E, Patel M, Cawley P, Heitner J, Crowley A, Elliott M, Parker M, Judd R, Kim R. Prevalence and Structural Risk Factors for Left Ventricular Thrombi in Patients with Systolic Dysfunction as Assessed by Cardiac MRI. American Heart Association 2004 (in process)
Comparative Diagnosis Utility of Color versus Monochromatic SPECT Image Display for Detection of Coronary Artery Disease.
Key Faculty: Jonathan Weinsaft, MD (Assistant Professor), Franklin Wong, MD (Assistant Professor), Massimiliano Szulc, PhD (Assistant Professor)
This study will provide important information regarding the optimal format for nuclear stress test interpretation. As a result, the findings of the study will improve the ability of nuclear stress testing to identify patients with important coronary disease. This study involves a Cardiology Fellow (Chris Gade, MD) and a Cardiac Cath attending (Robert Minutello, MD) for cardiac angiography correlation.
Selected References
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Cacciabaudo JM and Szulc M. Gated
Cardiac SPECT: has the addition of function to perfusion enhanced the
value of myocardial perfusion imaging? J Nucl Med. 2001;42:1050-52.
Jonathan W. Weinsaft, Franklin J. Wong, Jeff Walden, Massimiliano Szulc, Peter M Okin, Paul Kligfield. Anatomic Distribution of Myocardial Ischemia as a Determinant of Exercise-Induced ST Segment Depression. American Journal of Cardiology (in preparation)
